Trey Lance
Trey Lance will have one fewer weapon at his disposal in his first game as the full-time starter for the 49ers.
Tight end According to Adam Schefter of ESPN.com, George Kittle is slated to miss the regular-season debut against Chicago due to a groin ailment.
The injury was initially reported.
Kittle has been in good health throughout training camp and the preseason despite being listed as questionable. On Monday, the injury was initially reported. On Wednesday, Thursday, and Friday, he did not practice.
Charlie Woerner
Charlie Woerner is promoted to the starting lineup based on the team's unofficial depth chart. To No. 2, Ross Dwelley is promoted.
Woerner, a 2020 sixth-round pick, has participated in 33 games throughout the regular season. In 2021, he was a starter three times. He has eight catches for 88 yards in his career.
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